Arthros
GRIP Maternal protocol

RA Track

GRIP Maternal

RA — Pre-Conception, Pregnancy & PostpartumCompanion to GRIP

Duration

3 phases · Pre-Conception (≥3 mo), Pregnancy, Postpartum

Structure

Trimester-specific, companion to GRIP

Delivery

Virtual

About this protocol

GRIP Maternal is the reproductive-continuum companion to GRIP. The PreCARA study (2021) demonstrated 90.4% low disease activity or remission by the third trimester with modern treat-to-target care, while postpartum flares occur in 46.7% of patients within three months. The module integrates EULAR/BSR drug guidelines, ACOG Committee Opinion 804, and the 2019 Canadian Physical Activity in Pregnancy Guidelines — targeting methotrexate cessation 1–3 months pre-conception, certolizumab-friendly programming through pregnancy, and prompt postpartum exercise restart to combat the high-risk flare window.

Clinical authors

  • Angelo Papachristos, PT, ACPAC
  • Sameer Chunara, PT, ACPAC

Evidence base

GRIP Maternal is derived from systematic review and randomized controlled trial evidence in RA — Pre-Conception, Pregnancy & Postpartum. Protocol parameters — phase structure, load progression, and outcome measures — align with EULAR, ACR, and ASAS exercise-therapy recommendations. Outcome tracking favours open-access PROMIS instruments where validated equivalents exist.

View the evidence library →

Outcome measures

  • All GRIP core measures (PROMIS swaps applied)PROMIS
  • DAS28-CRP at 6 weeks postpartum (flare monitoring)
  • Grip strength (infant care demands)
  • Diastasis recti assessment at 6 weeks postpartum
  • DXA body composition at 6 months postpartum

PROMIS short forms are free, NIH-developed measures used in place of paid legacy instruments.

What's included

  • Virtual assessment with a certified exercise therapist
  • Personalised programme plan
  • Live-virtual group or individual sessions
  • Asynchronous guided home programme
  • Regular ePRO check-ins with adaptive progression
  • Care coordinator support
  • Programme completion report

Interested in this protocol?

Speak to us about adding GRIP Maternal to your PSP or benefits plan.

Request a pilotFor patients

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